Characterization and clinical evaluation of live influenza a vaccine prepared from a recombinant of the A/USSR/92/77 (H1N1) and the cold-adapted A/Ann Arbor/6/60 (H2N2) strains

Characterization and clinical evaluation of live influenza a vaccine prepared from a recombinant of the A/USSR/92/77 (H1N1) and the cold-adapted A/Ann Arbor/6/60 (H2N2) strains

Source :

• Antiviral Research [ 0166-3542 ] ; 1981.

Descripteurs français

• KwdFr :
  • Essais cliniques comme sujet, Génotype, Humains, Méthode en double aveugle, Production d'anticorps, Recombinaison génétique, Sous-type H1N1 du virus de la grippe A, Sous-type H2N2 du virus de la grippe A, Vaccins antigrippaux (immunologie), Vaccins antigrippaux (usage thérapeutique), Virus de la grippe A (génétique).
• MESH :
  • génétique : Virus de la grippe A.
  • immunologie : Vaccins antigrippaux.
  • usage thérapeutique : Vaccins antigrippaux.
  • Essais cliniques comme sujet, Génotype, Humains, Méthode en double aveugle, Production d'anticorps, Recombinaison génétique, Sous-type H1N1 du virus de la grippe A, Sous-type H2N2 du virus de la grippe A.

English descriptors

• KwdEn :
  • Antibody Formation, Clinical Trials as Topic, Double-Blind Method, Genotype, Humans, Influenza A Virus, H1N1 Subtype, Influenza A Virus, H2N2 Subtype, Influenza A virus (genetics), Influenza Vaccines (immunology), Influenza Vaccines (therapeutic use), Recombination, Genetic.
• MESH :
  • chemical , immunology : Influenza Vaccines.
  • genetics : Influenza A virus.
  • chemical , therapeutic use : Influenza Vaccines.
• Teeft :
  • Antibody Formation, Antibody response, Antibody responses, Antibody titres, Attenuated, Biomedical press, Body temperature, Calculation purposes, Chnical study, Clinical Trials as Topic, Clinical signs, Clone, Coarse spray, Donor strain, Double infection, Double-Blind Method, Febrile reactions, First vaccination, Genes coding, Genetic recombination, Genotype, Growth properties, Healthy volunteers, Humans, Influenza, Influenza A Virus, H1N1 Subtype, Influenza A Virus, H2N2 Subtype, Influenza vaccine, Influenza vaccines, Influenza virus, Influenza virus vaccine, Influenza viruses, Maassab, Mdck cells, More days, Nasal, Nasal swabs, Original vaccine virus, Parent strain, Placebo, Placebo group, Placebo response, Recombinant, Recombination, Recombination, Genetic, Sandoz research institute, Second vaccination, Seed virus, Serum antibody response, Serum level, Shutoff temperature, Study population, Stuffy nose, Surface proteins, Swab, Third blood sample, Tract symptoms, Undetectable antibody, Unwanted effects, Vaccination, Vaccine, Vaccine group, Vaccine virus, Virus, Volunteer.

Abstract

• https://api.istex.fr/ark:/67375/6H6-4JF1JL7T-W/fulltext.pdf

Affiliations:

• Pays-Bas

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